Sovitj Pou: search on Z-Library

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1

Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

Potharaju, Suresh, Mutyam, Shravan Kumar, Liu, Mingtao, Green, Carol, Frueh, Lisa, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Riscoe, Michael K., Shankar, Gita

Journal:

Pharmaceutical Development and Technology

Year:

2020

File:

PDF, 1.14 MB

2020

2

Use of the spin trap 4-POBN to detect low levels of hydroxyl radical in biological systems

Sovitj Pou, Carroll L. Ramos, Myron S. Cohen, Michael Jones, Gerald Rosen

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 122 KB

english, 1990

3

Use of deuterium-containing spin traps to enhance sensitivity of a low frequency electron paramagnetic resonance spectrometer: Implications for spin trapping free radicals, In Vivo

Howard J. Halpern, Sovitj Pou, Miroslav Peric, Eugene Barth, Gerald M. Rosen

Journal:

Free Radical Biology and Medicine

Year:

1990

File:

PDF, 96 KB

1990

4

Kinetics of spin trapping no- by iron-chelates and in vivo pharmacodynamics of the corresponding spin trapped adducts

Supatra Porasuphatana, Howard J. Halpern, Pei Tsai, Eugene D. Barth, G.V.R. Chandramouli, Sovitj Pou, Gerald M. Rosen

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 144 KB

english, 1998

5

Mechanism of Free-Radical Generation by Nitric Oxide Synthase

Rosen, Gerald M., Tsai, Pei, Pou, Sovitj

Journal:

Chemical Reviews

Year:

2002

Language:

english

File:

PDF, 161 KB

english, 2002

6

Is There Stereoselectivity in Spin Trapping Superoxide by 5- tert -Butoxycarbonyl-5-methyl-1-pyrroline N -Oxide?

Tsai, Pei, Marra, Jeffrey M., Pou, Sovitj, Bowman, Michael K., Rosen, Gerald M.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

7

Application of Spin Trapping to Human Phagocytic Cells: Insight Into Conditions for Formation and Limitation of Hydroxyl Radical

Cohen, Myron S., Britigan, Bradley E., Pou, Sovitj, Rosen, Gerald M.

Journal:

Free Radical Research

Year:

1991

Language:

english

File:

PDF, 517 KB

english, 1991

8

The Single-Dose Pharmacokinetics of Midazolam and Its Primary Metabolite in Pediatric Patients after Oral and Intravenous Administration

Reed, Michael D., Rodarte, Alexander, Blumer, Jeffrey L., Khoo, Ko-Chin, Akbari, Bardia, Pou, Sovitj, Kearns, Gregory L.

Journal:

Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

9

Effect of anti-inflammatory drugs on myeloperoxidase-dependent hydroxyl radical generation by human neutrophils

Carroll L. Ramos, Sovitj Pou, Gerald M. Rosen

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 763 KB

english, 1995

10

Design of modified pyrroline N-oxide derivatives as spin traps specific for hydroxyl radical

Arya, Prabhat, Stephens, J. Campbell, Griller, David, Pou, Sovitj, Ramos, Carroll L., Pou, Wanida S., Rosen, Gerald M.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 657 KB

english, 1992

11

Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria

Frueh, Lisa, Li, Yuexin, Mather, Michael, Li, Qigui, Pou, Sovitj, Nilsen, Aaron, Winter, Rolf W., Forquer, Isaac, Pershing, April, Xie, Lisa H., Smilkstein, Martin J., Caridha, Diana, Campbell, Robert

Journal:

ACS Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

12

Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro

Huang, Yu-Ing, Surichamorn, Wanida, Cao, Guan-Liang, Meng, Min, Pou, Sovitj, Rosen, Gerald M., Salcedo, Theodora W., Strimpler, Anne, Veale, Chris, Bernstein, Peter R., Bonuccelli, Catherine M.

Journal:

Journal of Leukocyte Biology

Year:

1998

Language:

english

File:

PDF, 95 KB

english, 1998

13

Spin trapping of hydroxyl radical by 2H-imidazole-1-oxides

Pei Tsai, Sovitj Pou, Gerald M. Rosen

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 72 KB

english, 1998

14

Light-dependent spin trapping of hydroxyl radical from human erythrocytes

Leon A. Bynoe, Sovitj Pou, John D. Gottsch, Gerald M. Rosen

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 436 KB

english, 1991

15

Investigations into the spin trapping of nitric oxide and superoxide: models to explore free radical generation by nitric oxide synthase

Tsai, Pei, Porasuphatana, Supatra, Pou, Sovitj, Rosen, Gerald M.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

2000

Language:

english

File:

PDF, 167 KB

english, 2000

16

Spin trapping of nitric oxide by ferro-chelates: kinetic and in vivo pharmacokinetic studies

Sovitj Pou, Pei Tsai, Supatra Porasuphatana, Howard J. Halpern, G.V.R. Chandramouli, Eugene D. Barth, Gerald M. Rosen

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1999

Language:

english

File:

PDF, 245 KB

english, 1999

17

1,3-Di(2-[5-3H]tolyl)guanidine: A Selective Ligand that Labels σ -Type Receptors for Psychotomimetic Opiates and Antipsychotic Drugs

Eckard Weber, Mark Sonders, Merrit Quarum, Stafford McLean, Sovitj Pou and John F. W. Keana

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 984 KB

english, 1986

18

Evaluation of various spin traps for the in vivo in situ detection of hydroxyl radical

Tsai, Pei, Pou, Sovitj, Straus, Rebecca, Rosen, Gerald M.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

19

Phagocyte-Derived Free Radicals Stimulated by Ingestion of Iron-Rich Staphylococcus aureus: A Spin-Trapping Study

Myron S. Cohen, Bradley E. Britigan, Yaachov S. Chai, Sovitj Pou, Thomas L. Roeder and Gerald M. Rosen

Journal:

The Journal of Infectious Diseases

Year:

1991

Language:

english

File:

PDF, 1.46 MB

english, 1991

20

Nitroxides as potential contrast enhancing agents for MRI application: Influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate

John F. W. Keana, Sovitj Pou, Gerald M. Rosen

Journal:

Magnetic Resonance in Medicine

Year:

1987

Language:

english

File:

PDF, 642 KB

english, 1987

21

A pseudoreceptor docking study of 4,5-α-epoxymorphinans with a range of dielectric constants

Rick Gussio, Sovitj Pou, Jih-Hsiang Chen, Gary W. Smythers

Journal:

Journal of Computer-Aided Molecular Design

Year:

1992

Language:

english

File:

PDF, 590 KB

english, 1992

22

Synthesis and properties of some nitroxide .alpha.-carboxylate salts

Keana, John F. W., Pou, Sovitj, Rosen, Gerald M.

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 571 KB

english, 1989

23

A targeted structure-activity analysis of endochin-like quinolones reveals potent Q i and Q o site inhibitors of Toxoplasma gondii and Plasmodium falciparum cytochrome bc 1 and identifies ELQ-400 as a remarkably effective compound against acute experimental toxoplasmosis.

McConnell, Erin V., Bruzual, Igor, Pou, Sovitj, Winter, Rolf W., Dodean, Rozalia A., Smilkstein, Martin J., Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N., Riscoe, Michael K., Doggett, J. Stone

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 2.96 MB

english, 2018

24

The insertion and extrusion of heterosulfur bridges. XII. Selectivity and side reactions in the bridging process

L. H. Klemm, Sovitj Pou, W. D. Detlefsen, Clay Higgins, Ross F. Lawrence

Journal:

Journal of Heterocyclic Chemistry

Year:

1984

File:

PDF, 289 KB

1984

25

Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-quinolone-3-diarylethers and Antimycin in Toxoplasma gondii

Alday, P. Holland, Bruzual, Igor, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Ben Mamoun, Choukri, Riscoe, Michael K, Doggett, J. Stone

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 722 KB

english, 2016

26

ChemInform Abstract: Mechanism of Free-Radical Generation by Nitric Oxide Synthase

Gerald M. Rosen, Pei Tsai, Sovitj Pou

Journal:

Year:

2002

File:

PDF, 24 KB

2002

27

Issues Pertinent to the in Vivo in Situ Spin Trapping of Free Radicals §

Pou, Sovitj, Halpern, Howard J., Tsai, Pei, Rosen, Gerald M.

Journal:

Accounts of Chemical Research

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

28

l-Arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide

Pei Tsai, John Weaver, Guan Liang Cao, Sovitj Pou, Linda J. Roman, Anatoly A. Starkov, Gerald M. Rosen

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

29

LIGHT-DEPENDENT GENERATION OF SUPEROXIDE FROM HUMAN ERYTHROCYTES

Leon A. Bynoe, John D. Gottsch, Sovitj Pou, Gerald M. Rosen

Journal:

Photochemistry and Photobiology

Year:

1992

Language:

english

File:

PDF, 423 KB

english, 1992

30

EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores

Wanida S. Pou, Sovitj Pou, Gerald M. Rosen, Esam E. El-Fakahany

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 142 KB

english, 1990

31

Use of a Low-Frequency Esr Spectrometer: Implications for Spin-Trapping Free Radicals, In Situ

Pou, Sovitj, Perk, Miroslav, Halpern, Howard J., Rosen, Gerald M.

Journal:

Free Radical Research

Year:

1991

Language:

english

File:

PDF, 492 KB

english, 1991

32

Application of Spin Traps to Biological Systems

Rosen, Gerald M., Cohen, Myron S., Britigan, Bradley E., Pou, Sovitj

Journal:

Free Radical Research

Year:

1990

Language:

english

File:

PDF, 508 KB

english, 1990

33

Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis

Foss, Marie H., Pou, Sovitj, Davidson, Patrick M., Dunaj, Jennifer L., Winter, Rolf W., Pou, Sovijja, Licon, Meredith H., Doh, Julia K., Li, Yuexin, Kelly, Jane X., Dodean, Rozalia A., Koop, Dennis R.

Journal:

ACS Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 2.87 MB

english, 2016

34

SYNTHESIS OF TWO PHOTOLABILE BENZYL MANGANESE DERIVATIVES INCORPORATING A GEOMETRICALLY INACCESSIBLE RADICAL TRAP

Keana, John F. W., Pou, Sovitj

Journal:

Organic Preparations and Procedures International

Year:

1989

Language:

english

File:

PDF, 315 KB

english, 1989

35

Spin-trapping of superoxide by 5,5-dimethyl-1-pyrroline N-oxide: Application to isolated perfused organs

Sovitj Pou, Gerald M. Rosen

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 545 KB

english, 1990

36

Intracellular spin-trapping of oxygen-centered radicals generated by human neutrophils

Pou, Sovitj, Rosen, Gerald M., Britigan, Bradley E., Cohen, Myron S.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1989

Language:

english

File:

PDF, 547 KB

english, 1989

37

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

Smilkstein, Martin J., Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A., Dodean, Rozalia A., Frueh, Lisa, Hinrichs, David J., Li, Yuexin, Martinson, Thomas, Munar, Myrna Y., Winter, Rolf W., Bruzual,

Journal:

Malaria Journal

Year:

2019

Language:

english

File:

PDF, 1.72 MB

english, 2019

38

Synthesis of deuterium- and nitrogen-15-containing pyrroline 1-oxides: a spin-trapping study

Pou, Sovitj, Rosen, Gerald M., Wu, Yexin, Keana, John F. W.

Journal:

Journal of Organic Chemistry

Year:

1990

Language:

english

File:

PDF, 708 KB

english, 1990

39

Influence of Conformation on the EPR Spectrum of 5,5-Dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl: A Spin Trapped Adduct of Superoxide

Rosen, Gerald M., Beselman, Aleksandra, Tsai, Pei, Pou, Sovitj, Mailer, Colin, Ichikawa, Kazuhiro, Robinson, Bruce H., Nielsen, Robert, Halpern, Howard J., MacKerell, Alexander D.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 190 KB

english, 2004

40

Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Lawres, Lauren A., Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P., Renard, Isaline, Virji, Azan Z., Boulard, Pierre, Rodriguez, Eduardo X., Allen, Alexander J., Pou, Sovitj, Wegmann, K

Journal:

Journal of Experimental Medicine

Year:

2016

Language:

english

File:

PDF, 2.13 MB

english, 2016

41

ChemInform Abstract: Issues Pertinent to the in vivo in situ Spin Trapping of Free Radicals

Sovitj Pou, Howard J. Halpern, Pei Tsai, Gerald M. Rosen

Journal:

Year:

1999

File:

PDF, 24 KB

1999

42

Endothelial cell mediated enhanced killing of Staphlococcus aureus following anoxia/reoxygenation

Roman E. Ratych, Jing Li, Michael A. Jones, Sovitj Pou, Gerald M Rosen

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 127 KB

english, 1990

43

A comparative study of neuronal and inducible nitric oxide synthases: Generation of nitric oxide, superoxide, and hydrogen peroxide

John Weaver, Supatra Porasuphatana, Pei Tsai, Sovitj Pou, Linda J. Roman, Gerald M. Rosen

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2005

Language:

english

File:

PDF, 270 KB

english, 2005

44

Conformational, Aqueous Solvation, and pKa Contributions to the Binding and Activity of Cocaine, WIN 35 065-2, and the WIN Vinyl Analog

Yang, Biao, Wright, Jeremy, Eldefrawi, Mohyee E., Pou, Sovitj, MacKerell, Alexander D.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

45

Generation of thiyl radical by nitric oxide: a spin trapping study

Pou, Sovitj, Rosen, Gerald M.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

46

Esters of 5-Carboxyl-5-methyl-1-pyrroline N -Oxide: A Family of Spin Traps for Superoxide

Tsai, Pei, Ichikawa, Kazuhiro, Mailer, Colin, Pou, Sovitj, Halpern, Howard J., Robinson, Bruce H., Nielsen, Robert, Rosen, Gerald M.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

47

Use of Nitroxides as NMR Contrast Enhancing Agents for Joints

Pou, Sovitj, Davis, Peter l., Wolf, Gerald L., Rosen, Gerald m.

Journal:

Free Radical Research

Year:

1995

Language:

english

File:

PDF, 798 KB

english, 1995

48

Problems associated with spin trapping oxygen-centered free radicals in biological systems

Sovitj Pou, Daniel J. Hassett, Bradley E. Britigan, Myron S. Cohen, Gerald M. Rosen

Journal:

Analytical Biochemistry

Year:

1989

Language:

english

File:

PDF, 660 KB

english, 1989

49

Detection and imaging of oxygen-centered free radicals with low-frequency electron paramagnetic resonance and signal-enhancing deuterium-containing spin traps

Halpern, Howard J., Pou, Sovitj, Peric, Miroslav, Yu, Cheng, Barth, Eugene, Rosen, Gerald M.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 823 KB

english, 1993

50

Discovery, Synthesis, and Optimization of Antimalarial 4(1 H )-Quinolone-3-Diarylethers

Nilsen, Aaron, Miley, Galen P., Forquer, Isaac P., Mather, Michael W., Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M., Stickles, Allison M., Ryan, Eileen, Kelly, Jane Xu, Doggett, J. St

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

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